蔡宗葦
發(fā)布時間:2011-04-10 閱讀次數(shù)：11595次
蔡宗葦，博士，教授，博士生導師。1982年廈門大學化學系獲得學士學位，1990年在德國University of Marburg獲得博士學位，1991-1994在美國University of Nebraska 質(zhì)譜研究中心從事博士后研究。1994-1996在美國University of Nebraska水質(zhì)中心任助理教授，2001年受聘于香港浸會大學，現(xiàn)為香港浸會大學化學系教授，二惡英分析實驗室主任。蔡宗葦教授是質(zhì)譜分析專家，從事質(zhì)譜的基礎理論和應用研究，特別善長于高分辨質(zhì)譜、GC-MS、LC-MS、CE-MS及其在環(huán)境、生物、藥物和痕量有機污染物分析方面的應用研究。蔡教授2003年獲得國家杰出青年基金，已在國際著名刊物上發(fā)表40多篇SCI論文，獲得的科學研究基金近千萬元，在生物質(zhì)譜研究領域取得了突出的成績。
Educational Background
* B.Sc., Xiamen University, China
* Ph.D., Marburg University, Germany
* Postdoctoral: University of Nebraska-Lincoln, USA
Professional Appointments
* Director of Dioxin Analysis Laboratory
* Associate Director of The Joint Institute of Environmental Sciences of Hong Kong Baptist University and The Research Center for Eco-Environmental Sciences, The Chinese Academy of Sciences
Current Research Interests
* Fundamentals and applications of mass spectrometry;
* high resolution mass spectrometry;
* Nanospray ESI-MS; GC-, LC- and CE-MS for environmental, biological, pharmaceutical and Chinese medicinal analyses;
* trace analysis of dioxins and persistent organic pollutants.
Selected Publications
1. Ning Liu, Wenjun Song, Pui Wang, Kim-Chung Lee, Zongwei Cai, Honglin Chen, "Identification of Unusual Truncated Forms of Nucleocapsid Protein in MDCK Cells Infected by Avian Influenza Virus (H9N2)", Proteomics, 10, 1875-1879 (2010).
2. Shuhai Lin, Wan Chan, Jinhua Li and Zongwei Cai, "Liquid chromatography/mass spectrometry for investigating the biochemical effects induced by aristolochic acid in rats: the plasma metabolome", Rapid Commun. Mass Spectrom., 24, 1312-1318 (2010).
3. Minghua Lu, Lan Zhang, Xin Li, Qiaomei Lu, Guonan Chen, Zongwei Cai, "A new method for the analysis of β2-agonists in human urine by pressure-assisted capillary electrochromatography coupled with electrospray ionization-mass spectrometry using a silica-based monolithic column", Talanta, 81, 1655-1661 (2010).
4. Lin Guo, Hao Yue, Zongwei Cai, "A novel pre-column fluorescent derivatization method for the sensitive determination of aristolochic acids in medicinal herbs by high-performance liquid chromatography with fluorescence detection", J. of Pharmaceutical and Biomedical Analysis, 53, 37-42 (2010).
5. Tianxiu Qian, Zongwei Cai, "Biotransformation of ginsenosides Rb1, Rg3 and Rh2 in rat gastrointestinal tracts", Chinese Medicine, 5, 19-26 (2010).
6. Ning Liu, Genyan Huang, Yi Guan, Kimchung Lee, Honglin Chen, Zongwei Cai, “Mutations in Influenza Virus Replication and Transcription: Detection of Amino Acid Substitutions in Hemagglutinin of an Avian Influenza Virus (H1N1)”, FASEB Journal, 23, 3377-3382 (2009).
7. Jun Wang, Tao Lin, Jiaping Lai, M.S. Yang, Zongwei Cai, “Analysis of Adenosine Phosphates in HepG-2 Cell by a HPLC-ESI-MS System with Porous Graphitic Carbon as Stationary Phase”, J. Chromatogr. B, 877, 2019-2024 (2009).
8. Jinhua Li, Wan Chan, Zongwei Cai, “On-line CE-ESI-MS Analysis of Urinary Porphyrins”, Electrophoresis, 30, 1790-1797 (2009).
9. Ning Liu, Wan Chan, Kim-Chung Lee, Zongwei Cai , “A Method to Enhance a1 Ions and Application for Peptide Sequencing and Protein Identification”, J. Am. Soc. Mass Spectrom., 20, 1214-1223 (2009).
10. Ning Liu, Kim-Chung Lee, Wenjun Song, Pui Wang, Honglin Chen, Zongwei Cai, “Identification of Amino Acid Substitutions in Mutated Peptides of Nucleoprotein from Avian Influenza Virus”, Talanta, 78, 1492-1496 (2009).
11. Wan Chan, Wing Tat Poon, Yan-Wo Chan, King-Yi Wan, Zongwei Cai, “A New Aproach for the Sensitive Determination of DNA Adduct of Aristolochic Acid II by Using HPLC with Fluorescence Detection”, J. Chromatogr. B, 877, 848-852 (2009).
12. Hao Yue, Wan Chan, Lin Guo, Zongwei Cai, “Determination of Aristolochic Acid I in Rat Urine and Plasma by HPLC with Fluorescence Detection”, J. Chromatogr. B, 877, 995-999 (2009).